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Updated: Nov 18, 2025

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Our experience of total pericardiectomy for constrictive pericarditis: a comprehensive analysis over a period of 5
Manish Jadhao1, Kuntal Surana1, Vijay Shewale1
1Department of Cardiovascular and Thoracic Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Insights
Surgical pericardiectomy offers favorable short-term outcomes for constrictive pericarditis (CP), improving functional class in most survivors despite some operative mortality.
Area of Science:
- Cardiology
- Thoracic Surgery
- Internal Medicine
Background:
- Constrictive pericarditis (CP) results from pericardial thickening and calcification, reducing cardiac output.
- Surgical pericardiectomy is a key treatment for CP, despite limited comparative studies.
Purpose of the Study:
- To identify predictors of morbidity and mortality associated with pericardiectomy.
- To evaluate the short-term surgical outcomes of pericardiectomy for CP in a single center.
Main Methods:
- Retrospective analysis of 30 patients undergoing isolated pericardiectomy (2013-2018).
- Procedures involved median sternotomy and total pericardiectomy without cardiopulmonary bypass.
- Pre-, intra-, and post-operative data were collected and analyzed.
Main Results:
- 60% of patients were male; 15 had a history of tuberculosis.
- Most patients presented with NYHA class III/IV; preoperative CVP decreased significantly post-surgery.
- 30-day mortality was 6.66%; low-cardiac output syndrome was the main morbidity. 26 patients showed improved NYHA status.
Conclusions:
- Pericardiectomy for CP has associated operative mortality but yields favorable short-term results.
- The surgery significantly improves functional class in the majority of surviving patients.
Introduction:
Constrictive pericarditis (CP) usually presents as a result of chronic fibrous pericardial thickening and calcification of the pericardium which causes reduced cardiac output. Despite the lack of prospective studies comparing the different therapeutic strategies, surgical pericardiectomy is a valuable treatment under most circumstances.
Aim:
We analyzed our records to highlight the predictors of morbidity and mortality of pericardiectomy and also short-term surgical outcome of the same procedure in a single center.
Material And Methods:
We carried out a comprehensive retrospective analysis of the records of patients who underwent surgery for CP at our institute between 2013 and 2018. 30 patients underwent isolated pericardiectomy. All patients underwent median sternotomy and total pericardiectomy without the use of cardiopulmonary bypass. Pre-operative, intra-operative and post-operative characteristics were noted.
Results:
Fifteen patients had a history of pulmonary tuberculosis. The majority of the patients presented with NYHA grade III or IV. 60% of the patients were male. The preoperative mean central venous pressure was 24 ±9 mm Hg and decreased to 9 ±5 mm Hg after surgery. The 30-day mortality was 6.66% (2/30). Morbidity was mainly due to low-cardiac output syndrome (n = 4). A total of 26 patients had significant improvement in their NYHA status.
Conclusions:
Although pericardiectomy for CP remains associated with some operative mortality, the short-term outcome is favorable, and surgical treatment is able to improve the functional class in the majority of survivors.
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