Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Posttraumatic pulmonary insufficiency: a treatable disease.

T J Gallagher, J M Civetta, R R Kirby

    Southern Medical Journal
    |November 1, 1977
    PubMed
    Summary

    Early aggressive treatment for posttraumatic pulmonary insufficiency using positive end-expiratory pressure (PEEP) and cardiovascular support successfully reversed respiratory failure in 39 patients. This approach proved effective regardless of trauma type, preventing deaths from respiratory complications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Population dynamics in lesser black-backed gulls in the Netherlands support a North Sea regime shift.

    Biology letters·2013
    Same author

    North Sea ecosystem change from swimming crabs to seagulls.

    Biology letters·2012
    Same author

    Warm-water decapods and the trophic amplification of climate in the North Sea.

    Biology letters·2010
    Same author

    A blooming jellyfish in the northeast Atlantic and Mediterranean.

    Biology letters·2010
    Same author

    The SceneScore for improved pre-hospital triage of motor-vehicle crash victims.

    Annual proceedings. Association for the Advancement of Automotive Medicine·2008
    Same author

    Intensive care.

    Current opinion in anaesthesiology·2006

    Area of Science:

    • Critical Care Medicine
    • Pulmonary Medicine
    • Trauma Surgery

    Background:

    • Posttraumatic pulmonary insufficiency presents a significant challenge in critical care.
    • Early identification of intrapulmonary shunt is crucial for timely intervention.

    Purpose of the Study:

    • To evaluate the efficacy of early aggressive treatment for posttraumatic pulmonary insufficiency.
    • To assess the impact of positive end-expiratory pressure (PEEP) and cardiovascular support on patient outcomes.

    Main Methods:

    • Treatment initiated when intrapulmonary shunt exceeded 15%, prior to severe hypoxemia, CO2 retention, or radiographic infiltrates.
    • Utilized positive end-expiratory pressure (PEEP) up to 40 cm H2O and comprehensive cardiovascular support.
    • Compared interventions for blunt versus penetrating trauma.

    Related Experiment Videos

    Main Results:

    • All 39 patients experienced reversal of respiratory failure, with shunt reduced to 15%.
    • 28 patients required aggressive interventions including high PEEP levels and cardiovascular support.
    • Blunt trauma patients required interventions for a longer duration than penetrating trauma patients.
    • No deaths occurred due to respiratory failure or treatment modalities.

    Conclusions:

    • Early, aggressive management of posttraumatic pulmonary insufficiency is effective and safe.
    • This treatment strategy successfully reverses respiratory failure and prevents mortality.
    • The approach allows for better differentiation of the severity of the initial traumatic insult.