Adrenal Pheochromocytoma Treated With Stereotactic Body Radiation Therapy

Pheochromocytoma is a rare neuroendocrine tumor arising from chromaffin cells in the adrenal medulla. In most cases, it is benign and tends to remain localized. However since it leads to the development of cardiovascular disease, it is associated with high rates of morbidity and mortality. Treatment options include medical, surgical, or ablative measures, which often adequately control the disease. Primary pheochromocytoma is conventionally treated with external beam radiation therapy (EBRT), while stereotactic body radiation therapy (SBRT) is preferred for cases with metastasis. However, literature regarding the use of SBRT for the treatment of primary disease is scarce. This case report describes a patient with an inoperable primary adrenal gland pheochromocytoma who was treated with SBRT, resulting in adequate symptomatic control during clinical follow-up.