A robust study on 2019-nCOV outbreaks through non-singular derivative

Muhammad Altaf Khan1,2, Saif Ullah3, Sunil Kumar4

  • 1Informetrics Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam.

European Physical Journal Plus
|February 8, 2021
PubMed

Insights

This study introduces a novel fractional mathematical model for COVID-19 dynamics using the Atangana-Baleanu derivative. The model helps understand disease transmission and control strategies, emphasizing the importance of memory effects.

Area of Science:

  • Epidemiology
  • Mathematical Biology
  • Fractional Calculus

Background:

  • The global impact of the COVID-19 pandemic necessitates advanced modeling approaches.
  • Existing models may not fully capture the complex dynamics and memory effects inherent in disease transmission.

Purpose of the Study:

  • To develop and analyze a new fractional mathematical model for COVID-19.
  • To investigate the influence of memory effects and model parameters on disease transmission and control.
  • To establish the global asymptotic stability of the disease-free equilibrium.

Main Methods:

  • Formulation of an integer-order model and its generalization using the Atangana-Baleanu fractional derivative with a non-singular kernel.
  • Analysis of essential mathematical properties of the fractional model.
  • Application of a nonlinear fractional Lyapunov function for stability analysis.
  • Numerical solution using an efficient modified Adams-Bashforth scheme.

Main Results:

  • The study presents a generalized fractional model for COVID-19 dynamics.
  • Demonstration of the global asymptotic stability at the disease-free equilibrium.
  • Numerical simulations highlight the impact of the memory index and model parameters on infection spread and control.

Conclusions:

  • The developed Atangana-Baleanu fractional model provides deeper insights into COVID-19 transmission dynamics.
  • The memory index plays a crucial role in understanding and managing the pandemic.
  • The findings support the development of effective control strategies for infectious diseases.

Related Concept Videos

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
17.3K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
342
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
713
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.2K
Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
37.5K
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
326