Rapid and Green Fabrication of Carbon Dots for Cellular Imaging and Anti-Counterfeiting Applications

Carbon dots (CDs) with plenty of favorable properties have been extensively investigated in diverse areas including bioimaging, biomedicine, sensor, energy storage, anti-counterfeiting, photocatalysis, and optoelectronic devices. Herein, a simple, rapid, and green sonochemical-assisted method for fabricating nitrogen-doped CDs has been developed. In this approach, the nitrogen-doped CDs can be obtained through irradiation by intensive ultrasonic waves from ultrasonic probes in 30 min. The achieved CDs exhibit excellent water dispersibility, which can be ascribed to their high functionalization. Importantly, the CDs also demonstrate remarkable fluorescent properties, high photostability, and low cytotoxicity, which can be utilized for multicolor cellular imaging and anti-counterfeiting applications. As far as we know, the sonochemical-assisted method for rapidly synthesizing nitrogen-doped CDs from gelatin has never been reported before. Significantly, the sonochemical-assisted approach to rapidly fabricate CDs is versatile for the facile construction of fluorescent CDs, and the obtained CDs can be potentially used in various areas including bioimaging and anti-counterfeiting.