Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatigue in multiple sclerosis.

L B Krupp1, L A Alvarez, N G LaRocca

  • 1Department of Neurology, Albert Einstein College of Medicine, Bronx, NY.

Archives of Neurology
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Report of Phoma exigua var. heteromorpha Causing Oleander Dieback in Spain.

Plant disease·2019
Same author

Lavender Cotton Root Rot: A New Host of Phytophthora tentaculata Found in Spain.

Plant disease·2019
Same author

First Report of Leaf Spot and Twig Blight of Rhododendron spp. Caused by Phytophthora hibernalis in Spain.

Plant disease·2019
Same author

First Report of Leaf Spot, Blight, and Stem Lesions Caused by Cylindrocladium pauciramosum on Callistemon in Spain.

Plant disease·2019
Same author

Bleeding Canker on Mesquite in Peru caused by Phytophthora syringae.

Plant disease·2019
Same author

Comparison of Application Methods of Systemic Fungicides to Suppress Branch Cankers in Clementine Trees Caused by Phytophthora citrophthora.

Plant disease·2019
Same journal

Incorrect Table Entries and Word.

Archives of neurology·2016
Same journal

IDEAL for CCSVI Research-Reply.

Archives of neurology·2013
Same journal

Atlas of Inherited Metabolic Diseases, 3rd ed.

Archives of neurology·2013
Same journal

Error in byline: in heterogeneity of coenzyme q10 deficiency: patient study and literature review.

Archives of neurology·2013
Same journal

This month in archives of neurology.

Archives of neurology·2013
Same journal

About this journal.

Archives of neurology·2013
See all related articles

Multiple sclerosis (MS) fatigue is more frequent and severe than in healthy adults. This disabling symptom is distinct from depression or general impairment, suggesting it

Area of Science:

  • Neurology
  • Clinical Psychology

Background:

  • Fatigue is a common and debilitating symptom in multiple sclerosis (MS).
  • The underlying causes and characteristics of MS fatigue are not well understood.
  • Its relationship with other MS symptoms requires further investigation.

Purpose of the Study:

  • To investigate the frequency, severity, and characteristics of fatigue in patients with MS.
  • To differentiate MS fatigue from normal fatigue, depression, and general neurological impairment.

Main Methods:

  • Conducted structured interviews with 32 patients diagnosed with MS.
  • Interviewed 33 healthy adults as a control group.
  • Assessed fatigue, depression, and global impairment levels.

Main Results:

Related Experiment Videos

  • Fatigue was significantly more frequent and severe in the MS patient group compared to healthy controls.
  • MS fatigue showed no correlation with depression.
  • MS fatigue was independent of global neurological impairment.

Conclusions:

  • Multiple sclerosis fatigue is a distinct clinical entity.
  • It is often disabling and can be differentiated from normal fatigue, affective disturbances, and neurological impairment.
  • Further research into MS fatigue mechanisms and management is warranted.