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Two-photon excited peptide nanodrugs for precise photodynamic therapy
Hongqian Cao1, Yanfei Qi, Xibao Gao
1School of Public Health, Shandong University, Jinan, Shandong, China.
Chemical Communications (Cambridge, England)
|February 8, 2021
Abstract:
A novel peptide nanodrug composed of three functional motifs, bis(pyrene), FFVLK and CREKA, was used as a two-photon excited photosensitizer for precise photodynamic therapy (PDT). The system presented excellent two-photon imaging ability, tumor target effect and high reactive oxygen species productivity for improving treatment precision and efficiency in PDT.
