Related Experiment Video
Updated: Nov 18, 2025
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Effect of endovascular treatment on high-risk patients with chronic carotid artery occlusion
Insights
Endovascular treatment for chronic carotid artery occlusion in high-risk patients is safe and effective. This procedure shows significant short-to-mid-term curative effects, improving neurological function.
Area of Science:
- Vascular Surgery
- Interventional Neurology
- Cardiovascular Research
Background:
- Chronic carotid artery occlusion presents a significant risk for stroke.
- Identifying safe and effective treatments for high-risk patients is crucial.
- Endovascular approaches offer a minimally invasive alternative for managing complex arterial occlusive diseases.
Purpose of the Study:
- To evaluate the safety and short-term efficacy of endovascular treatment.
- To assess treatment outcomes in high-risk patients with chronic carotid artery occlusion.
- To analyze neurological function improvement and adverse events post-procedure.
Main Methods:
- Retrospective analysis of 16 high-risk patients with 100% carotid artery stenosis.
- Endovascular treatment performed between November 2013 and July 2016.
- Assessment of adverse events and neurological function (NIHSS) at various follow-up intervals (1 week to 6 months).
Main Results:
- Successful revascularization achieved in most cases, significantly reducing stenosis (100% to 24.9%).
- Low incidence of major adverse events, with some cases requiring alternative treatments or experiencing transient complications.
- Significant improvement in NIHSS scores (2.0 ± 1.36) six months post-procedure compared to pre-operation.
Conclusions:
- Endovascular treatment is a safe and effective option for high-risk patients with chronic carotid artery occlusion.
- The treatment demonstrates notable curative effects in the short to mid-term.
- This approach can lead to significant neurological recovery in carefully selected patient cohorts.
Objective:
This study aims to discuss the safety and short-term efficacy of endovascular treatment on high-risk patients with chronic carotid artery occlusion.
Methods:
A retrospective analysis was performed on the clinical data of 16 high-risk patients with chronic carotid artery occlusion who received endovascular treatment at the Department of Neurosurgery of the First Affiliated Hospital of Xinjiang Medical University from November 2013 to July 2016. The incidence of adverse events at 1 week, 30 days and six months post-operation were observed, and NIHSS was adopted to assess the neurological function of patients six months before and after the operation. Follow-up time was 6-26 months, with an average of 18.4 months.
Results:
The degree of carotid artery stenosis of these 16 patients was 100%. The degree of which after the operation was 24.9 ± 17.0%; and the difference was statistically significant (P<0.05). Iatrogenic carotid artery dissection occurred in one case, and persistent hypotension and sinus bradycardia occurred in one case. Furthermore, one case of endovascular treatment was not approved to be opened. Afterwards, temporal artery-STA-MCA bypass was performed; upon postoperative head CTA and DSA, the result showed that the perfusion was good. One case refused to undergo surgical treatment. The NHSS score of 14 cases of endovascular treatment that were successfully opened six months after the operation was 2.0 ± 1.36, which improved (P<0.05) compared with that of pre-operation.
Conclusion:
Endovascular treatment on high-risk patients with chronic carotid artery occlusion is safe and effective. And it has obvious curative effect in short mid-term.
Key Words:
Arterial occlusive disease, Carotid artery, Endovascular treatment, Treatment outcome.
More Related Videos
09:36A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
Published on: August 12, 2025
06:53A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
