Related Experiment Videos
Myosin heavy chain composition of single fibres from normal human muscle
D Biral1, R Betto, D Danieli-Betto
1Centro del C.N.R. per lo Studio della Biologia e Fisiopatologia Muscolare, Università di Padova, Italy.
The Biochemical Journal
|February 15, 1988
Abstract:
Electrophoretic analysis in the presence of 33% glycerol of purified myosin from normal human muscle shows three distinct protein bands which are identified as type 1, 2B, and 2A myosin heavy chain (MHC) isoforms by affinity-purified polyclonal antibodies. Analysis of MHC of single human muscle fibres shows that human muscles contain a large population of fibres showing the coexistence of type 2A and 2B MHC.