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Updated: Nov 18, 2025

Bioluminescent Orthotopic Model of Pancreatic Cancer Progression
Published on: June 28, 2013
Pancreatic cancer pathology viewed in the light of evolution
Michaël Noë1,2, Seung-Mo Hong3, Laura D Wood1,2
1Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, The Johns Hopkins University School of Medicine, Carnegie 415, 600 North Wolfe Street, Baltimore, MD, 21287, USA.
Abstract:
One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This "evolutionary view" creates both expected and surprising perspectives in all stages of neoplastic progression. Advances in the field will require greater attention to this critical evolutionary prospective.

