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Published on: December 7, 2012
Economic Analyses of Pathogen-Reduction Technologies in Blood Transfusion: A Systematic Literature Review
Patrick R LaFontaine1, Jing Yuan1, Katherine M Prioli2
1Center for Health Outcomes, Policy, and Economics, Rutgers University, 160 Frelinghuysen Road, Suite 417, Piscataway, NJ, 08854, USA.
Economic analyses of pathogen-reduction technologies (PRTs) show increased costs but variable effectiveness. Understanding these economic implications is crucial for optimizing blood transfusion safety and guiding the adoption of new bacterial risk-control strategies.
Area of Science:
- Transfusion Medicine
- Health Economics
- Public Health
Background:
- Pathogen reduction technologies (PRTs) are increasingly used in blood transfusion.
- Economic implications of PRTs are not well understood.
- New technologies and regulations necessitate updated economic reviews.
Conclusions:
- Economic outcomes depend heavily on existing screening protocols.
- Blood safety optimization may not align with typical pharmaceutical willingness-to-pay thresholds.
- Continued evidence generation with transparency is vital for informed decision-making on PRTs.
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