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Published on: May 10, 2022
Benefit of transaminase elevations in establishing functional cure of HBV infection during nap-based combination
Michel Bazinet1, Victor Pântea2, Gheorghe Placinta2
1Replicor Inc, Montréal, Canada.
Abstract:
Treatment of HBV infection with nucleic acid polymers and pegIFN is accompanied by transaminase elevations in 95% of participants. HBV viral rebound, partial cure (HBV DNA < 2000 IU/mL, normal ALT) or functional cure (HBV DNA target not detected, HBsAg
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