Related Experiment Video
Updated: Nov 18, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Prioritizing movement to address the frailty phenotype in heart failure
Deepika R Laddu1, Cemal Ozemek2, Ahmad Sabbahi1
1Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA.
Physical frailty is common in older adults with heart failure (HF). Exercise interventions targeting frailty may improve outcomes for these patients.
Area of Science:
- Gerontology
- Cardiology
- Physical Medicine
Background:
- Frailty is a prevalent syndrome in older adults with heart failure (HF), linked to poor prognosis and complex care.
- Physical frailty, characterized by muscle weakness, slowness, and low activity, is a critical indicator in older HF patients.
- Current exercise therapies for HF lack specific evidence for older, frail populations, highlighting a management gap.
Purpose of the Study:
- To enhance understanding of physical frailty in older adults with HF.
- To explore the relationship between physical frailty and HF care management.
- To discuss the implications of exercise and rehabilitation for managing frailty and improving outcomes in HF patients.
Main Methods:
- This is a review article, synthesizing existing literature.
- Focuses on the definition and assessment of physical frailty.
- Examines the role of exercise-based interventions in frail HF patients.
Main Results:
- Physical frailty is a key factor influencing clinical outcomes in older HF patients.
- Objective physical performance measures are crucial for assessing frailty.
- Interdisciplinary exercise interventions targeting frailty show promise.
Conclusions:
- Physical frailty requires specific consideration in the management of older heart failure patients.
- Movement-based interventions, including tailored exercise and rehabilitation, are vital for counteracting frailty.
- Addressing physical frailty can improve patient-centered outcomes in this population.
Related Concept Videos
Heart Failure V: Medical Management
Heart Failure VII: Nursing Interventions
Heart Failure II: Pathophysiology
Pathophysiology of Heart Failure
Heart Failure I: Introduction
Heart Failure VI: Adjunct Therapies

