Effect of Posterior Tracheopexy on Risk of Recurrence in Children after Recurrent Tracheo-Esophageal Fistula Repair

Ali Kamran1, Benjamin Zendejas1, Jay Meisner1

  • 1Departments of General Surgery, Boston Children's Hospital, Boston, MA.

Insights

Recurrent tracheo-esophageal fistula (TEF) in children can be effectively treated with posterior tracheopexy and rotational esophagoplasty. This surgical approach significantly reduces re-recurrence rates and improves patient outcomes.

Area of Science:

  • Pediatric Surgery
  • Thoracic Surgery
  • Gastroenterology

Background:

  • Recurrent tracheo-esophageal fistula (TEF) is a challenging complication following initial repair of esophageal atresia and TEF.
  • Existing therapeutic options have variable success rates and high re-recurrence rates, hindering optimal treatment selection.
  • Limited data from small cohorts and short follow-up periods complicate the assessment of treatment efficacy.

Purpose of the Study:

  • To evaluate the effectiveness of posterior tracheopexy combined with rotational esophagoplasty for treating recurrent TEF.
  • To assess the operative risks and long-term outcomes associated with this surgical technique.
  • To determine the re-recurrence rate after surgical management of recurrent TEF.

Main Methods:

  • A retrospective review of 62 patients with recurrent TEF treated between 2011 and 2020 at two institutions.
  • Surgical intervention involved dividing the TEF, performing posterior tracheopexy (suturing trachea to spine), and rotational esophagoplasty.
  • Endoscopic surveillance was used to monitor for re-recurrence during follow-up.

Main Results:

  • Sixty-two patients underwent surgical treatment for recurrent TEF at a median age of 14 months, with all presenting significant respiratory symptoms.
  • Twenty-four patients had prior failed endoscopic or surgical repairs; 29 required concomitant esophageal stricture management.
  • No recurrences were observed during a median follow-up of 2.5 years, with complete resolution of symptoms and low perioperative morbidity (3 esophageal leaks, 1 vocal cord dysfunction).

Conclusions:

  • Posterior tracheopexy and rotational esophagoplasty represent a highly effective surgical strategy for recurrent TEF.
  • This combined surgical approach significantly prevents re-recurrence of TEF.
  • The procedure is associated with low perioperative morbidity, offering a favorable long-term outcome for affected children.
Abstract

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