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Effect of methylene blue on the absorbance of solutions of haemoglobin
1Department of Anesthesia, Harvard Medical School, Boston, MA.
British Journal of Anaesthesia
|March 1, 1988
Abstract:
The effect of the i.v. administration of methylene blue dye on haemoglobin oxygen saturation, measured by a pulse oximeter was investigated. The absorption spectra of various concentrations of haemoglobin, oxyhaemoglobin and methylene blue were compared. The amount of 660-nm light absorbed by methylene blue was sufficient to cause a factitious haemoglobin desaturation as measured by the pulse oximeter.