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Is Submucosal Injection Helpful in Cold Snare Polypectomy for Small Colorectal Polyps?
Ji Hyun Song1, Shai Friedland2,3
1Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Clinical Endoscopy
|February 9, 2021
Summary
Submucosal injection did not significantly impact outcomes for cold snare endoscopic mucosal resection (CS-EMR) in small colorectal polyps. Cold snare polypectomy (CSP) and CS-EMR showed similar complete resection and bleeding rates.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
- Colorectal Surgery
Background:
- Cold snare polypectomy (CSP) is established for small colorectal polyp removal.
- The role of submucosal injection in cold snare endoscopic mucosal resection (CS-EMR) for small polyps remains unclear.
Purpose of the Study:
- To evaluate the impact of submucosal injection in CS-EMR for small colorectal polyps (5-10 mm).
Main Methods:
- A comparative study of 100 small colorectal polyps in 58 patients.
- 50 polyps removed via CS-EMR, 50 via CSP.
- Collected data included demographics, procedure details, and outcomes.
Main Results:
- No significant difference in complete resection rates between CS-EMR and CSP.
- Bleeding rates were comparable between the two techniques.
- Warfarin and direct-acting oral anticoagulants increased bleeding risk.
Conclusions:
- Submucosal injection does not significantly alter outcomes for CSP in small colorectal polyps.
- CS-EMR and CSP demonstrate similar efficacy and safety profiles for small polyps.

