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Recovery of cutaneous immune responsiveness after PUVA therapy
S I White1, P S Friedmann, C Moss
1Department of Dermatology, University of Newcastle upon Tyne, U.K.
The British Journal of Dermatology
|March 1, 1988
Abstract:
We studied sensitization to dinitrochlorobenzene (DNCB) in psoriatic patients before, during and 2, 4, and 6 weeks after a course of photochemotherapy (PUVA). The inhibition of sensitivity observed during PUVA was completely reversed after 6 weeks. Thus the PUVA-mediated inhibition of cutaneous immune responsiveness is of short duration. However, whether there are long-term sequelae remains to be established.