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Lifestyle Intervention in Chronic Ischaemic Heart Disease and Type 2 Diabetes (the LeIKD study): study protocol of a

Pia von Korn1,2, Hanna Sydow3,4, Sarah Neubauer5

  • 1Department of Prevention and Sports Medicine, Technical University of Munich, Munchen, Germany.

BMJ Open
|February 9, 2021
PubMed

Insights

This study investigates a telemedical lifestyle intervention for patients with chronic ischemic heart disease and type 2 diabetes. The goal is to improve cardiovascular risk factors and health outcomes compared to usual care.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Lifestyle interventions are recommended for chronic ischemic heart disease (CIHD) and type 2 diabetes mellitus (T2DM).
  • Randomized controlled trial evidence is limited for patients with both CIHD and T2DM.

Purpose of the Study:

  • To evaluate if a telemedical lifestyle intervention (LS) is superior to usual care (UC) in patients with CIHD and T2DM.
  • To assess the impact of LS on cardiovascular risk factors, physical activity, quality of life, and health economics.

Main Methods:

  • Prospective, multicenter randomized trial (LeIKD study) comparing LS and UC (1:1 ratio).
  • LS includes 6 months of exercise, nutritional counseling, and telemedicine support, followed by 6 months of monitoring.
  • Primary endpoint: change in HbA1c from baseline to 6 months.

Main Results:

  • Study is ongoing; results are not yet available.

Conclusions:

  • The LeIKD trial will provide crucial evidence on the efficacy of telemedical lifestyle interventions for comorbid CIHD and T2DM.
  • Findings may inform clinical guidelines and healthcare strategies for managing patients with these combined conditions.
Abstract

Keywords:
coronary heart diseasediabetes & endocrinologyhealth economicsischaemic heart diseasepreventive medicinesports medicine

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