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Risk assessment and prognostic aspect of coagulopathy in COVID-19

Mujibur Rahman1, Nadira Naznin Rakhi2

  • 1Department of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.

Advances in Respiratory Medicine
|February 9, 2021
PubMed

Insights

The COVID-19 pandemic has led to increased blood clotting issues (coagulopathy), raising mortality risks. Understanding these coagulation changes in severe cases is crucial for effective patient management and improved outcomes.

Area of Science:

  • * Hematology and Infectious Diseases: Investigating the intersection of viral infections and blood coagulation disorders.

Background:

  • * The global spread of SARS-CoV-2 (COVID-19) has resulted in a pandemic with significant morbidity and mortality.
  • * COVID-19 patients frequently exhibit blood coagulopathy, contributing to organ dysfunction and increased fatality rates.

Discussion:

  • * Alterations in coagulation function due to COVID-19 elevate the risk of pulmonary embolism and deep vein thrombosis.
  • * Elevated D-dimer levels and fibrin degradation products are commonly observed, particularly in severe COVID-19 cases.

Key Insights:

  • * COVID-19 significantly impacts blood coagulation, leading to life-threatening thrombotic events.
  • * Severe COVID-19 cases show distinct coagulopathy patterns compared to non-severe cases, necessitating tailored treatment approaches.

Outlook:

  • * Further research is needed to elucidate the precise mechanisms of COVID-19-induced coagulopathy.
  • * Developing targeted management strategies for COVID-19-related coagulation disorders is essential for improving patient prognosis and reducing mortality.

Keywords:
COVID-19D-dimerblood coagulopathyembolismthrombosis

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