Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus

Alexander Lin1, Ovidiu Andronesi2, Wolfgang Bogner3

  • 1Center for Clinical Spectroscopy, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

NMR in Biomedicine
|February 9, 2021
PubMed

Insights

Standardizing Magnetic Resonance Spectroscopy (MRS) methods is crucial for clinical practice. This paper offers minimum guidelines and a checklist to improve reporting, reproducibility, and meta-analysis of MRS studies.

Area of Science:

  • Biomedical Imaging
  • Medical Physics
  • Neuroimaging

Background:

  • Magnetic Resonance Spectroscopy (MRS) shows clinical potential but faces challenges in translation due to inconsistent technical methods.
  • Variations in MRS acquisition, post-processing, and analysis significantly impact result interpretation.
  • Incomplete reporting of methodological details hinders standardized assessment, manuscript review, and study reproducibility.

Purpose of the Study:

  • To establish minimum guidelines for reporting MRS methods and results.
  • To address the lack of technical standardization in MRS research.
  • To facilitate the consistent and reproducible application of MRS in clinical settings.

Main Methods:

  • A consensus group of Magnetic Resonance Spectroscopy (MRS) experts convened to define reporting standards.
  • Guidelines were developed for the standardized description of MRS hardware, data acquisition, analysis, and quality assessment.
  • A checklist was created to aid authors, reviewers, and editors in ensuring comprehensive MRS study reporting.

Main Results:

  • Minimum guidelines for reporting MRS methods and results have been established.
  • A detailed checklist is provided to assist in the standardized reporting of MRS studies.
  • The guidelines cover hardware, acquisition, analysis, and quality assessment aspects of MRS.

Conclusions:

  • Standardized reporting of MRS methods is essential for advancing its clinical translation.
  • The proposed guidelines and checklist aim to enhance the quality, reproducibility, and comparability of MRS studies.
  • Adoption of these standards will facilitate manuscript review, reproducibility, and meta-analyses in the field of MRS.

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