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Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus
Alexander Lin1, Ovidiu Andronesi2, Wolfgang Bogner3
1Center for Clinical Spectroscopy, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details are often not fully reported, making it difficult to assess MRS studies on a standardized basis. This hampers the reviewing of manuscripts, limits the reproducibility of study results, and complicates meta-analysis of the literature. In this paper a consensus group of MRS experts provides minimum guidelines for the reporting of MRS methods and results, including the standardized description of MRS hardware, data acquisition, analysis, and quality assessment. This consensus statement describes each of these requirements in detail and includes a checklist to assist authors and journal reviewers and to provide a practical way for journal editors to ensure that MRS studies are reported in full.
Insights
Standardizing Magnetic Resonance Spectroscopy (MRS) methods is crucial for clinical practice. This paper offers minimum guidelines and a checklist to improve reporting, reproducibility, and meta-analysis of MRS studies.
Area of Science:
- Biomedical Imaging
- Medical Physics
- Neuroimaging
Background:
- Magnetic Resonance Spectroscopy (MRS) shows clinical potential but faces challenges in translation due to inconsistent technical methods.
- Variations in MRS acquisition, post-processing, and analysis significantly impact result interpretation.
- Incomplete reporting of methodological details hinders standardized assessment, manuscript review, and study reproducibility.
Purpose of the Study:
- To establish minimum guidelines for reporting MRS methods and results.
- To address the lack of technical standardization in MRS research.
- To facilitate the consistent and reproducible application of MRS in clinical settings.
Main Methods:
- A consensus group of Magnetic Resonance Spectroscopy (MRS) experts convened to define reporting standards.
- Guidelines were developed for the standardized description of MRS hardware, data acquisition, analysis, and quality assessment.
- A checklist was created to aid authors, reviewers, and editors in ensuring comprehensive MRS study reporting.
Main Results:
- Minimum guidelines for reporting MRS methods and results have been established.
- A detailed checklist is provided to assist in the standardized reporting of MRS studies.
- The guidelines cover hardware, acquisition, analysis, and quality assessment aspects of MRS.
Conclusions:
- Standardized reporting of MRS methods is essential for advancing its clinical translation.
- The proposed guidelines and checklist aim to enhance the quality, reproducibility, and comparability of MRS studies.
- Adoption of these standards will facilitate manuscript review, reproducibility, and meta-analyses in the field of MRS.
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