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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

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[Whether or not to treat pregnant women with an SSRI]

M W Kooter-Nugteren1, B F P Broekman2,3

  • 1OLVG, afd. Psychiatrie, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|February 9, 2021
PubMed

In this article the dilemma of prescribing antidepressants during pregnancy is elucidated. Based on a case of a pregnant woman with a history of depressive disorder we discuss how to weigh the benefits and risks of prescribing antidepressant medication. On the one hand the possible effects of antidepressants on both the pregnancy as well as on the fetus are pointed out, while on the other hand the possible effects of an (untreated) depressive disorder on the course of the pregnancy and the development of the offspring are also explained. We conclude how the benefits and risks have to be discussed with the patient and preferably also her partner, in view of shared decision making.

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