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Comparative immunochemical and structural similarities of five stress proteins from various tissue types

J L Pipkin1, J F Anson, W G Hinson

  • 1Department of Health and Human Services, National Centre for Toxicological Research, Jefferson, Arkansas 72079.

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
|January 1, 1988
PubMed

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Protein Families02:47

Protein Families

Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key locations, protein...