Related Experiment Video
Updated: Nov 18, 2025

Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Emerging Technologies in Cardiac Pacing From Leadless Pacers to Stem Cells
Michael Lawren Co1, John Paul Khouzam2, Issa Pour-Ghaz3
1Department of Cardiology, Loma Linda University Medical Center, Loma Linda, CA.
Abstract:
Modern pacemakers can sense and pace multiple chambers of the heart. These pacemakers have different modes and features to optimize atrioventricular synchrony and promote intrinsic conduction. Despite recent advancements, current pacemakers have several drawbacks that limit their feasibility. In this review article, we discuss several of these limitations and detail several emerging technologies in cardiac pacing aimed to solve some of these limitations. We present several technological advancements in cardiac pacing, including the use of leadless pacemakers, physiologic pacing, battery improvements, and bioartificial pacemakers. More research still needs to be done in testing the safety and efficacy of these new developments.

