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Human alpha 2-HS-glycoprotein localized to 3q27----q29 by in situ hybridization
V L Magnuson1, J L McCombs, C C Lee
1Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio 78284.
Cytogenetics and Cell Genetics
|January 1, 1988
Abstract:
Human plasma protein alpha 2-HS-glycoprotein (AHSG) is composed of two polypeptide chains, A and B, encoded by a single mRNA. Southern blot analysis of mouse x human somatic cell hybrids has mapped the AHSG gene to human chromosome 3 in the region 3q21----qter (Lee et al., 1987). Using a recombinant plasmid containing a 1,538 bp insert spanning the entire AHSG coding region, AHSG was localized to chromosomal bands 3q27----q29 by in situ hybridization.