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Published on: January 4, 2019
Platelet-Rich Plasma Injection in Patients with Atrophic Rhinitis
Do Hyun Kim1, Min Hyeong Lee1, Jaeyoon Lee1
1Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Objective:
To investigate the effect of platelet-rich plasma (PRP) injection in patients with atrophic rhinitis.
Methods:
Prepared PRP was injected into the inferior turbinate bilaterally, and nasal bacterial cultures were conducted. Improvement of symptoms was assessed with the Nasal Obstruction Symptom Evaluation (NOSE) and the Sino-Nasal Outcome Test-22 (SNOT-22). Nasal mucociliary clearance was assessed using the saccharin transit time (STT).
Results:
In the PRP-injected group (group A), NOSE (throughout the study) and SNOT-22 (1 month after injection) scores were significantly decreased during the study. However, the saline spray group (group B) showed no significant nasal symptom improvement during the study period. In group A, the STT was improved until 3 months after the injection. In contrast, group B showed STT improvement after 2 months that was maintained throughout the study.
Conclusion:
PRP injections can improve nasal symptoms and nasal mucociliary function in patients with atrophic rhinitis.
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