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Carbon Nanotubes: Probabilistic Approach for Occupational Risk Assessment
Andrea Spinazzè1, Carolina Zellino1, Francesca Borghi1
1Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell'Insubria, Via Valleggio, 11-22100 Como, Italy.
Nanomaterials (Basel, Switzerland)
|February 10, 2021
Summary
This study assessed occupational risks from carbon nanotubes (CNTs) using a probabilistic approach. While all work events showed risk, manufacturing CNT films without local exhaust ventilation presented a statistically significant risk.
Area of Science:
- Occupational health and safety
- Nanomaterial risk assessment
- Environmental science
Background:
- Carbon nanotubes (CNTs) are increasingly used in various industries.
- Assessing occupational exposure risks is crucial for worker safety.
- Previous studies provide data on chronic and subchronic inhalation of CNTs.
Purpose of the Study:
- To conduct an occupational risk assessment for carbon nanotubes (CNTs) via a probabilistic approach.
- To evaluate risks associated with different work events in CNT production.
- To determine the probability of relevant occupational risk occurrence.
Main Methods:
- Hazard identification using chronic and subchronic inhalation exposure studies.
- Derivation of a guidance value (BMC h) for occupational inhalation exposure to CNTs.
- Probabilistic risk assessment using exposure scenarios and risk characterization ratios (RCRs).
Main Results:
- A guidance value (BMC h) was established as a lognormal distribution (10.0 ± 4.2 µg/m³).
- Three work events (WEs) related to conductive film production were analyzed.
- All WEs showed RCR distributions ≥ 1, indicating risk; WE2 (no LEV) was statistically significant.
Conclusions:
- The probabilistic approach effectively characterizes occupational risks associated with CNTs.
- Manufacturing CNT films without local exhaust ventilation poses a significant occupational risk.
- Risk management strategies, such as implementing LEV, are essential in CNT handling environments.

