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Updated: Nov 18, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Same rhythm, different song-approaches to atrial fibrillation management by cardiologists and nephrologists
Patrick B Mark1, Lucia Del Vecchio2, Jose M Valdivielso3
1Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Insights
Atrial fibrillation (AF) is common in patients with chronic kidney disease (CKD). Management strategies for AF in advanced CKD patients lack evidence, necessitating improved collaboration between nephrologists and cardiologists.
Area of Science:
- Nephrology and Cardiology
- Clinical Management of Atrial Fibrillation in Chronic Kidney Disease
Background:
- Atrial fibrillation (AF) affects 10-25% of dialysis patients, who face higher stroke risks.
- Limited evidence exists for AF management (rate/rhythm control, anticoagulation) in advanced CKD.
- Randomized controlled trials are lacking for AF management in this population.
Discussion:
- A survey revealed differing management approaches between nephrologists and cardiologists for AF in CKD.
- Specialists identified challenges including healthcare burden, clinic proximity to dialysis sites, and CKD-specific treatment complications.
- Enhanced collaboration is crucial for optimizing patient outcomes.
Key Insights:
- Significant evidence gaps exist for managing AF in advanced CKD.
- Divergent clinical practices between nephrology and cardiology highlight a need for integrated care.
- Patient-centered care must address logistical and treatment-specific challenges.
Outlook:
- Future research should focus on evidence generation for AF management in CKD.
- Interdisciplinary collaboration is essential for developing standardized, effective treatment guidelines.
- Addressing patient burden and CKD-specific risks will improve AF management in this vulnerable population.
Abstract:
Atrial fibrillation (AF) is common in patients with chronic kidney disease (CKD), affecting 10-25% of patients requiring dialysis. Compared with the general population, patients requiring dialysis are also at increased risk of stroke, the major thromboembolic complication of AF. The evidence base for management strategies of AF specific to patients with advanced CKD is limited and not informed by randomized controlled trials. These gaps in evidence encompass rate and rhythm control strategies as well as a paucity of data informing which patients should receive anticoagulation. The European Renal Association-European Dialysis and Transplant Association and European Heart Rhythm Association undertook a survey of nephrologists and cardiologists exploring management strategies in patients with AF and CKD. We review the results of this survey, highlighting the differences in clinical approaches from cardiologists and nephrologists to these conditions. Closer collaboration between these specialties should lead to improved outcomes for patients with advanced CKD and AF. Specific issues that will need to be addressed may include healthcare burden to patients, location of clinics compared with dialysis sites and awareness of complications of treatments specific to CKD, such as calciphylaxis associated with vitamin K antagonism.
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