Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Muscle Performance01:27

Exercise and Muscle Performance

2.1K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.1K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

3.5K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.5K
Proteins: Dietary Sources and Requirements01:28

Proteins: Dietary Sources and Requirements

1.1K
Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
1.1K
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

2.9K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
2.9K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

1.6K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
1.6K
Protein Digestion01:02

Protein Digestion

108.9K
Protein digestion begins in the stomach, where the highly acidic environment can easily disrupt protein structure by exposing the peptide bonds of polypeptide chains. After polypeptide chains are broken into individual amino acids by a series of digestive enzymes, the amino acids are transported to the liver via the bloodstream to produce energy.
108.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sport-specific prevalence of Relative Energy Deficiency in Sport (REDs) risk among Finnish female national- and international-level athletes.

Journal of science and medicine in sport·2026
Same author

Eating attitudes and behaviors characteristics in high-level Kenyan female and male distance runners.

Frontiers in sports and active living·2026
Same author

Effects of Intensive Training on Prolactin Responses to Submaximal Exercise in Males.

The Journal of the Iowa Academy of Science : JIAS·2026
Same author

CHARACTERIZATION OF THE PROLACTIN RESPONSE TO PROLONGED ENDURANCE EXERCISE.

Acta kinesiologiae Universitatis Tartuensis·2026
Same author

REDs alert: male athletes be wary and scientists take action!

British journal of sports medicine·2023
Same author

Influence of resistance training and herbal supplementation on plasma apelin and metabolic syndrome risk factors in postmenopausal women.

Science & sports·2023

Related Experiment Video

Updated: Nov 18, 2025

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
08:03

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Published on: June 11, 2017

13.9K

Exercise, Dietary Protein, and Combined Effect on IGF-1.

C N Gulick1, M C Peddie2, T Jowett3

  • 1School of Physical Education, Sport & Exercise Sciences, University of Otago, PO Box 56, Dunedin 9054, New Zealand.

International Journal of Science and Research Methodology
|February 10, 2021
PubMed
Summary

Exercise acutely increased free Insulin-like Growth Factor 1 (IGF-1), while high protein meals elevated 24-hour IGF-1. Understanding these effects informs muscle growth and cancer risk management.

Keywords:
dietinsulin-like growth factorphysical activitysomatotropin

More Related Videos

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.1K
Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

42.0K

Related Experiment Videos

Last Updated: Nov 18, 2025

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
08:03

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Published on: June 11, 2017

13.9K
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.1K
Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

42.0K

Area of Science:

  • Endocrinology
  • Exercise Physiology
  • Nutritional Science

Background:

  • Insulin-like Growth Factor 1 (IGF-1) plays a dual role, promoting growth and repair but linked to increased cancer risk at high concentrations.
  • Dietary protein and exercise are known modulators of IGF-1 levels.

Purpose of the Study:

  • To investigate the acute effects and time-course of plasma free IGF-1 following dietary protein intake and/or exercise.
  • To provide data informing strategies for optimizing IGF-1 for muscle growth or mitigating risks associated with elevated IGF-1.

Main Methods:

  • A three-way crossover study involving 24 participants.
  • Conditions included a high-protein meal, exercise (sprint interval training), and exercise followed by a high-protein meal.
  • Plasma free IGF-1 was measured at baseline, immediately post-intervention, and over a 5-hour recovery period, plus a 24-hour follow-up.

Main Results:

  • Plasma free IGF-1 significantly increased immediately post-exercise in the exercise-only condition (p=0.04).
  • The high-protein meal condition resulted in a 17.5% increase in IGF-1 at 24 hours compared to baseline (p=0.02).
  • No significant changes in IGF-1 over time were observed in response to the combined exercise and protein condition.

Conclusions:

  • Acute exercise can transiently elevate free IGF-1, potentially benefiting muscle repair and hypertrophy.
  • Sustained high protein intake may lead to chronically elevated IGF-1, warranting further investigation into long-term health implications, including cancer risk.
  • Further research is needed to determine optimal timing and dosage of protein and exercise for specific health outcomes.