Related Experiment Video
Updated: Nov 18, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
A decade of surgical therapy in an all-comer cohort with type A aortic dissection
Jing Li1, Matthaeus Zerdzitzki2, Daniele Camboni2
1Department of Cardiothoracic Surgery, University Medical Center of Regensburg, Regensburg, Germany - jing.li@ukr.de.
Insights
This study analyzed a decade of aortic surgery for type A aortic dissection, revealing evolving techniques and outcomes. Refined surgical approaches are leading to more individualized treatment strategies for this complex condition.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Disease
Background:
- Type A aortic dissection poses significant surgical challenges.
- A decade of experience provides insights into evolving treatment paradigms.
Purpose of the Study:
- To assess surgical techniques and outcomes for type A aortic dissection over a 10-year period.
- To analyze an all-comer patient cohort at a university cardiosurgical center.
Main Methods:
- Retrospective statistical analysis of 283 patients undergoing surgical therapy for type A aortic dissection (2009-2018).
- Inclusion criteria encompassed all patients treated within the study period.
Main Results:
- Overall survival to discharge was 79.5%.
- Neurological deficit (18.9%) and malperfusion syndromes (extremity 17.4%, abdominal 8.2%) were significant concerns.
- Visceral malperfusion and heart failure requiring ECMO therapy were associated with increased mortality.
Conclusions:
- Surgery for type A aortic dissection remains complex.
- Surgical techniques and indications have evolved towards a more individualized treatment concept.
Background:
We reported on a decade of aortic surgery for type A aortic dissection to assess surgical techniques employed and outcomes over time in an all-comer analysis of a mid-size university cardiosurgical center.
Methods:
From 2009 to 2018, 283 patients (189 males and 94 females, mean age 62 years, range 30-85 years), who underwent surgical therapy for type A aortic dissection in our institution were included in a retrospective statistical analysis.
Results:
Among all the patients, 55.5% of them were hemodynamically stable, 10.3% came in intubated. A neurological deficit was present in 18.9% of cases, extremity malperfusion was noted in 17.4%, and abdominal malperfusion detected in 8.2%. The extent of the aortic dissection corresponded to DeBakey type I in 88% of cases, a thoracoabdominal involvement was seen in 64%. In 51.9% of patients, only the ascending aorta replaced, another 40.6% of patients had proximal arch replacement too. A separate stent placement into the descending aorta was achieved in 13.4% of patients, during surgery (5.7%) or thereafter (7.7%). Overall survival to discharge was 79.5%. Most frequent complications were stroke and paralysis (15.2%), but only visceral malperfusion (OR 9.0) and heart failure mandating ECMO therapy (OR 29.5) were associated with significantly increased mortality.
Conclusions:
Surgery for type A aortic dissection is still challenging. Along with the refinement of surgical techniques, the indication for the various procedures has moved from a simplified general strategy to a more individualized concept.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm IV: Nursing Management
Aortic Regurgitation III: Medical Management
