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Breakthrough Candidemia in Pediatric Patients With Cancer From a Brazilian Center
Anna Carlota Mott Barrientos1, João Nobrega de Almeida Junior2,3, Nadia Litvinov1
1From the Department of Pediatrics.
The Pediatric Infectious Disease Journal
|February 10, 2021
Abstract:
We analyzed 19 cases of breakthrough candidemia from a referral pediatric cancer center in Brazil. All patients had neutropenia and were under antifungal prophylactic regimens, mostly micafungin (68%). Most of the patients were treated with amphotericin B formulations and 30-day mortality was 21%. Candida parapsilosis was the main etiologic agent (63%), and horizontal transmission was not evidenced by microsatellite analysis.
