Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise training induces glycogen sparing during exercise by old rats.

G D Cartee1, R P Farrar

  • 1Department of Physical and Health Education, University of Texas, Austin 78712.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|January 1, 1988
PubMed
Summary

Exercise training improves glycogen sparing during intense exercise, and this benefit is maintained in older rats. Age does not diminish the effectiveness of training on glycogen utilization in muscles and the liver.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Akt substrate of 160 kDa dephosphorylation rate is reduced in insulin-stimulated rat skeletal muscle after acute exercise.

Physiological research·2017
Same author

The B2 receptor of bradykinin is not essential for the post-exercise increase in glucose uptake by insulin-stimulated mouse skeletal muscle.

Physiological research·2011
Same author

Attenuation of ethanol toxicity in primary myocardial cell cultures from offspring of swim-trained pregnant rats.

Toxicology in vitro : an international journal published in association with BIBRA·2010
Same author

Rapid reversal of insulin-stimulated AS160 phosphorylation in rat skeletal muscle after insulin exposure.

Physiological research·2009
Same author

Relationship between protein O-linked glycosylation and insulin-stimulated glucose transport in rat skeletal muscle following calorie restriction or exposure to O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate.

Acta physiologica Scandinavica·2005
Same author

Role of kallikrein-kininogen system in insulin-stimulated glucose transport after muscle contractions.

Journal of applied physiology (Bethesda, Md. : 1985)·2002

Area of Science:

  • Exercise Physiology
  • Aging Research
  • Metabolic Biochemistry

Background:

  • Muscle respiratory capacity and glycogen utilization are crucial for exercise performance.
  • Aging is associated with a decline in muscle respiratory capacity.
  • Exercise training can mitigate age-related declines in physiological functions.

Purpose of the Study:

  • To investigate the impact of age on glycogen utilization during exercise.
  • To determine if exercise training affects glycogen sparing similarly in young and old rats.
  • To compare liver and gastrocnemius glycogen concentrations in trained and untrained rats of different ages.

Main Methods:

  • Identically trained young (10 mo) and old (24 mo) Fischer 344 rats underwent a 6-month exercise protocol.

Related Experiment Videos

  • Animals were subjected to a 30-minute run at 75% maximal oxygen consumption.
  • Liver and gastrocnemius glycogen concentrations were measured at rest and post-exercise, compared to untrained controls.

    • Main Results:

    • Gastrocnemius glycogen was lower in untrained rats post-exercise compared to trained rats.
    • Estimated glycogen utilization during exercise was reduced in both trained young and old rats versus untrained controls.
    • Training-induced glycogen sparing during exercise was not diminished by age.

    Conclusions:

    • Exercise training enhances glycogen sparing during submaximal exercise.
    • The beneficial effects of training on glycogen utilization are preserved with aging.
    • Identically trained young and old rats exhibit similar glycogen sparing capacity.