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Comparisons of fatigue between dialysis modalities: A cross-sectional study
Yukio Maruyama1, Masaaki Nakayama2, Atsushi Ueda3
1Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Plos One
|February 10, 2021
Summary
Dialysis type does not significantly impact patient fatigue. Factors like age and employment status are more closely linked to fatigue severity in patients undergoing renal replacement therapy.
Area of Science:
- Nephrology
- Clinical Medicine
- Patient Outcomes
Background:
- Fatigue is a common complication in patients undergoing dialysis, negatively impacting outcomes.
- While several factors contribute to fatigue, the influence of different dialysis modalities remains unclear.
Purpose of the Study:
- To investigate the association between various dialysis modalities and the prevalence or severity of fatigue in patients with kidney disease.
Main Methods:
- A cross-sectional study included 194 dialysis patients (hemodialysis, online hemodiafiltration, peritoneal dialysis, combined therapy).
- Fatigue was assessed using multiple validated scales (POMS, VAS, original scale).
- Depression was evaluated using the Beck Depression Inventory-second edition (BDI-II).
Main Results:
- No significant differences in fatigue scores were observed across the four dialysis modalities.
- Multivariate analysis indicated age, BMI, creatinine, and employment status were associated with fatigue, not dialysis type.
- Fatigue was less prevalent on dialysis-free days for hemodialysis and online hemodiafiltration patients.
Conclusions:
- Dialysis modality (hemodialysis, online hemodiafiltration, peritoneal dialysis) is not significantly associated with fatigue prevalence or severity.
- Patient-specific factors beyond dialysis type are key determinants of fatigue in this population.
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