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Correlation between Cardiomegaly on Chest X-Ray and Left Ventricular Diameter on Echocardiography in Patients with

Matheus Rassi Fernandes Ramos1, Henrique Turin Moreira1, Gustavo Jardim Volpe1

  • 1Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Cardiologia, Ribeirão Preto, SP - Brasil.

Arquivos Brasileiros De Cardiologia
|February 10, 2021
PubMed

Insights

Left ventricular end-diastolic diameter (LVEDD) on echocardiography accurately identifies cardiomegaly in Chagas disease patients. This finding aids in risk stratification using the Rassi score, improving prognostic assessment for chronic Chagas cardiomyopathy.

Area of Science:

  • Cardiology
  • Radiology
  • Infectious Diseases

Background:

  • Cardiomegaly on chest X-ray predicts mortality in chronic Chagas cardiomyopathy (CCC).
  • The relationship between cardiothoracic ratio (CTR) on chest X-ray and left ventricular end-diastolic diameter (LVEDD) on echocardiography in CCC is not well-defined.

Purpose of the Study:

  • To evaluate the correlation between chest X-ray findings and LVEDD via echocardiography in Chagas disease patients.
  • To assess the applicability of this correlation to the Rassi score for risk stratification.

Main Methods:

  • Retrospective analysis of 63 Chagas disease outpatients.
  • Chest X-ray (cardiomegaly defined as CTR > 0.5) and echocardiography were performed.
  • Receiver Operating Characteristic (ROC) curve analysis determined LVEDD's ability to detect cardiomegaly.

Main Results:

  • The area under the ROC curve for LVEDD was 0.806, indicating good diagnostic performance.
  • An LVEDD cutoff of 60 mm demonstrated 64% sensitivity and 89% specificity for detecting cardiomegaly.
  • Using LVEDD as a surrogate for CTR altered the Rassi score in 14 patients, reducing perceived risk in 10.

Conclusions:

  • LVEDD measured by echocardiography is a reliable and highly specific indicator of cardiomegaly on chest X-ray in Chagas disease.
  • Echocardiographic LVEDD can serve as a valuable tool for assessing cardiomegaly and refining risk assessment in CCC.
Abstract

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