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Rickettsiales in Italy.

Cristoforo Guccione1, Claudia Colomba1,2, Manlio Tolomeo1

  • 1Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties- University of Palermo, 90127 Palermo, Italy.

Pathogens (Basel, Switzerland)
|February 11, 2021
PubMed
Summary

This study reviewed Rickettsiales in Italy, identifying 36 species. Six Rickettsiales species were found in humans, highlighting the need for routine molecular surveillance in tick-bite patients.

Keywords:
AnaplasmaEhrlichiaOrientiaRickettsiaRickettsiales

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Limited updated information exists regarding the prevalence of Rickettsiales in Italy.
  • Rickettsiales are a group of intracellular bacteria transmitted by arthropods, posing potential health risks.
  • Understanding their distribution in humans, vectors, and animal hosts is crucial for public health surveillance.

Purpose of the Study:

  • To provide an updated overview of Rickettsiales species identified in Italy.
  • To focus on Rickettsiales detected in humans, potential arthropod vectors, and animal hosts.
  • To assess the current situation of Rickettsiales in Italy using molecular identification methods.

Main Methods:

  • A comprehensive computerized literature search was performed using PubMed.
  • The search included studies published up to December 31, 2020, without language restrictions.
  • The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology guided the review process.

Main Results:

  • A total of 36 Rickettsiales species were identified across the reviewed literature.
  • Six species were detected in human tissues: Anaplasma phagocytophilum, Rickettsia conorii, R. conorii subsp. israelensis, R. monacensis, R. massiliae, and R. slovaca.
  • Various Rickettsiales species were also found in blood-sucking arthropods and potential animal hosts.

Conclusions:

  • The study identified specific Rickettsiales species in Italian human populations and potential transmission vectors.
  • Pathogens transmitted by arthropods may cause poorly characterized human diseases, necessitating further investigation.
  • Routine molecular detection of Rickettsiales in individuals with arthropod bites and in ticks is recommended for enhanced surveillance.