Related Experiment Video
Updated: Nov 18, 2025

Functional Characterization of Endogenously Expressed Human RYR1 Variants
Published on: June 9, 2021
More than myalgia: An unusual presentation of exertional rhabdomyolysis
Matthew O A Benedict1, Anthonio O Adefuye
1Department of Family Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein. benedictma@ufs.ac.za.
Abstract:
Exertional or exercise-induced rhabdomyolysis (ER) is a condition in which excessive and unaccustomed physical activity results in skeletal muscle damage. The ER is a relatively uncommon condition but can have very serious consequences such as acute renal failure, severe electrolyte abnormalities, acid base disturbances and death if not recognised and managed appropriately. The risk factors for rhabdomyolysis exist in our local setting, hence, it is paramount that healthcare practitioners (GPs) in our settings be made aware of ER, its prevention and symptoms. Cases of ER are often reported in sports men or women. Here, we report a case of a 33-year-old healthy female, with clinical and serological presentation, which is typical of ER following the commencement of a regimen of exercise to lose weight.
Related Concept Videos
Myocarditis II: Clinical Features and Diagnostic Tests
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Nephrotic Syndrome I : Introduction
Muscle Recovery and Fatigue
Acute Kidney Injury III: Clinical Manifestations
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...

