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Pain Control by Targeting Oxidized Phospholipids: Functions, Mechanisms, Perspectives

Beatrice Oehler1,2,3, Alexander Brack3, Robert Blum4

  • 1Wolfson Center of Age-Related Diseases, IoPPN, Health and Life Science, King's College London, London, United Kingdom.

Frontiers in Endocrinology
|February 11, 2021
PubMed
Summary

Oxidized phospholipids (OxPL) induce pain by activating specific neuronal channels. Targeting OxPL offers a potential therapeutic strategy for inflammatory and neuropathic pain syndromes.

Keywords:
TRP channelanalgesiaion channelmimetic peptidenociceptionoxidized phospholipidspain therapytherapeutic antibody

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