[Is the alpps procedure justified in children?]

Area of Science:

• Hepatobiliary Surgery
• Pediatric Surgery
• Surgical Oncology

Background:

• Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) is a complex two-stage surgical procedure.
• Its application in pediatric patients is less established compared to adults.

Purpose of the Study:

• To analyze current literature data on indications and outcomes of ALPPS in pediatric patients.
• To evaluate the feasibility of ALPPS in children based on existing evidence.

Main Methods:

• Comprehensive review of modern literature concerning ALPPS in pediatric cases.
• Analysis of reported indications, surgical outcomes, and complications.

Main Results:

• Limited data available on the specific application of ALPPS in pediatric populations.
• Inconclusive evidence regarding post-resection liver failure and future liver remnant (FLR) function in children undergoing ALPPS.

Conclusions:

• The current literature provides insufficient data to definitively establish the safety and efficacy of ALPPS in pediatric patients.
• Further research is needed to clarify the risks, benefits, and optimal management strategies for ALPPS in children, particularly concerning liver function and failure.