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Improving Human Health with Milk Fat Globule Membrane, Lactic Acid Bacteria, and Bifidobacteria

Erica Kosmerl1, Diana Rocha-Mendoza1, Joana Ortega-Anaya1

  • 1Department of Food Science and Technology, The Ohio State University, Columbus, OH 43210, USA.

Microorganisms
|February 12, 2021
PubMed

Insights

Milk fat globule membrane (MFGM) and probiotics show synergistic health benefits. Their interaction enhances gut function, immunity, and cognitive development, particularly in infants.

Area of Science:

  • Nutritional Science
  • Microbiology
  • Immunology

Background:

  • Milk fat globule membrane (MFGM) is recognized for its health benefits, including gut function, immune support, and cognitive development.
  • MFGM constituents can interact with probiotic bacteria like bifidobacteria and lactic acid bacteria (LAB) via bacterial surface proteins.

Purpose of the Study:

  • To review the synergistic effects of co-supplementing MFGM and probiotics.
  • To emphasize their interactions, colocalization in dairy foods, and supporting evidence.

Main Methods:

  • Literature review of in vivo and clinical studies.
  • Analysis of MFGM-probiotic interactions and their presence in dairy products.

Main Results:

  • Evidence supports a synergistic effect between MFGM and probiotics for human health across all age groups.
  • This synergy enhances probiotic survival and adhesion during gastrointestinal transit.
  • The combination positively impacts mucosal immunity and neurocognitive behavior in infants.

Conclusions:

  • Co-supplementation of MFGM and probiotics offers significant health advantages.
  • Further research into their interactions and applications is warranted.
Keywords:
dairy foodsgut microbiotainfant formulainteractionsmilk fat globule membrane

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