Related Experiment Video
Updated: Nov 17, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Differential Nonenrollment of Taiwanese Children in School-Based Substance Use Prevention Studies: A Multilevel
Chuan-Yu Chen1,2, Carla L Storr3, Jen-Huoy Tsay4,5
1Institute of Public Health, National Yang-Ming University, Taiwan.
Objective:
The present study investigated the extent to which individual and school characteristics may differentially affect parental consent and child assent in the enrollment of a school-based substance use prevention study in Taiwan.
Method:
This study linked field notes on response and consent status during enrollment of the school-based prevention study with administrative survey data reported by the targeted students when they were in fourth grade (age 10-11) (N = 2,560; 53% male, 97.8% matched). The outcome variables, defined by the combined status of parental consent/child assent, were nonresponse and negative, discordant, and positive consent. Individual characteristics included family (parental education, employment) and child (psychological/behavioral, substance use) factors. Aggregate school-level substance use and percentage of aboriginal students and nonnative parents served as school-level factors. Multilevel multinomial regression analyses were performed.
Results:
Successful consent was obtained from only 820 students (32%). Male gender and feeling neglected by families were associated with failing to respond (adjusted odds ratio = 1.78 and 1.71, respectively). Higher parental educational attainment reduced the odds of negative consent by 30%, whereas having unemployed parents increased the odds of discordant consent by 326%. Children attending schools with a higher percentage of indigenous students were two times more likely to have nonresponse, negative consent, and discordant consent.
Conclusions:
Nonresponse to the consent request or negative consent appeared to be associated with disadvantaged background and unfavorable parent-child interaction. This suggests complex pathways underlying ascertainment and a need to modify the consent practices in school-based prevention studies involving minors, especially in schools with higher ethnic minority composition.
More Related Videos
Related Concept Videos
Longitudinal Research
Analysis of Population Pharmacokinetic Data
Mechanistic Models: Compartment Models in Individual and Population Analysis
Longitudinal Studies
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Statistical Methods for Analyzing Epidemiological Data

