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[Study of the role of conditionally pathogenic enterobacteria in acute intestinal diseases]
Abstract:
Conditionally pathogenic enterobacteria were isolated in 34.2% of the patients with acute intestinal diseases (1559 cases examined in all). Such representatives of enterobacteria as Klebsiella, Hafnia, Citrobacter of 4, 8, and 22 serological groups. Proteus mirabilis of 6, 10, 13, 26, and 28 serological groups, and Proteus morganii mostly played the etiological role. In some of the patients conditionally pathogenic microbes only aggravated the main disease, taking part in the development of dysbacteriosis. In healthy individuals these microbes were much more rare and were encountered inconstantly.
Insights
Conditionally pathogenic enterobacteria were found in over a third of patients with acute intestinal diseases. These microbes, including Klebsiella and Proteus, often worsened symptoms and caused dysbacteriosis.
Area of Science:
- Microbiology
- Infectious Diseases
- Gastroenterology
Background:
- Enterobacteria are common gut microbes, but some strains can cause disease.
- Acute intestinal diseases have various causes, including bacterial infections.
- The role of specific enterobacterial strains in disease etiology needs further clarification.
Purpose of the Study:
- To determine the prevalence of conditionally pathogenic enterobacteria in patients with acute intestinal diseases.
- To identify specific enterobacterial species and serological groups involved in these infections.
- To understand the contribution of these microbes to disease severity and dysbacteriosis.
Main Methods:
- Microbiological isolation and identification of enterobacteria from patient samples.
- Serological grouping of isolated enterobacteria strains.
- Clinical data analysis to correlate microbial findings with disease presentation.
Main Results:
- Conditionally pathogenic enterobacteria were isolated from 34.2% of 1559 patients with acute intestinal diseases.
- Key etiological agents included Klebsiella, Hafnia, Citrobacter (specific serogroups), Proteus mirabilis (specific serogroups), and Proteus morganii.
- These microbes were less common and inconstant in healthy individuals.
Conclusions:
- Conditionally pathogenic enterobacteria play a significant role in the etiology of acute intestinal diseases.
- Specific serogroups of Klebsiella, Hafnia, Citrobacter, Proteus mirabilis, and Proteus morganii are frequently implicated.
- These bacteria can exacerbate primary infections and contribute to the development of dysbacteriosis.