Related Experiment Video
Updated: Nov 17, 2025
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.3K
Fast Stent Retrieval during Mechanical Thrombectomy Improves Recanalization in Patients with the Negative
S Soize1,2, J-B Eymard2, S Cheikh-Rouhou2
1From the Unité Mixte de recherche-S U1237 (S.S., M.Z., E.T.), Institut National de la Santé et de la Recherche Médicale, Normandie University , Université Caen-Normandie, Cyceron, Caen, France ssoize@chu-reims.fr.
AJNR. American Journal of Neuroradiology
|February 12, 2021
Summary
Fast stent retrieval during mechanical thrombectomy improves recanalization rates for fibrin-rich clots in acute ischemic stroke patients with the negative susceptibility vessel sign. This faster technique is safe and effective for clot removal.
Area of Science:
- Neurology
- Interventional Radiology
- Biomedical Engineering
Background:
- Fibrin-rich clots, indicated by the negative susceptibility vessel sign on T2*-weighted images, pose challenges in acute ischemic stroke treatment.
- In vitro studies suggest fast stent retrieval enhances the extraction of these difficult clots.
Purpose of the Study:
- To evaluate the impact of stent retrieval speed on recanalization and clinical outcomes in acute ischemic stroke patients with the negative susceptibility vessel sign.
- To determine if faster stent retrieval improves outcomes in mechanical thrombectomy for specific clot types.
Main Methods:
- Retrospective analysis of 68 acute ischemic stroke patients undergoing mechanical thrombectomy (January 2016-January 2020).
- Inclusion criteria: anterior circulation occlusion (Internal Carotid Artery-L, M1, M2), negative susceptibility vessel sign, and combined stent retriever + contact aspiration technique within 8 hours of onset.
- Patients were stratified into fast versus slow stent retrieval groups; primary outcome was first-pass recanalization rate.
Main Results:
- Fast retrieval was used in 31 (45.6%) patients, showing significantly higher odds of first-pass and final complete, near-complete, and successful recanalization.
- No significant differences were observed in procedure-related serious adverse events, distal embolization, or symptomatic intracranial hemorrhage between groups.
- Functional independence and all-cause mortality at 90 days did not differ significantly between fast and slow retrieval groups.
Conclusions:
- Fast stent retrieval is a safe and effective method for improving clot retrieval in patients with the negative susceptibility vessel sign during mechanical thrombectomy.
- Accelerated retrieval techniques may enhance treatment efficacy for specific clot compositions in acute ischemic stroke.
