Protocol for a randomised clinical trial of multimodal postconcussion symptom treatment and recovery: the Concussion

Vicki Anderson1,2,3, Vanessa C Rausa4, Nicholas Anderson4

  • 1Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia vicki.anderson@rch.org.au.

BMJ Open
|February 12, 2021
PubMed

Insights

A new multimodal intervention effectively treats persistent postconcussive symptoms (pPCS) in children, accelerating recovery and improving outcomes. This approach tailors treatment to individual symptoms, offering a promising solution for pediatric concussion recovery.

Area of Science:

  • Pediatric neurology
  • Clinical psychology
  • Rehabilitation medicine

Background:

  • Persistent postconcussive symptoms (pPCS) affect approximately 30% of children beyond one month after concussion.
  • Current treatments for pPCS often use unimodal approaches, despite evidence suggesting pPCS result from interacting symptom clusters.

Purpose of the Study:

  • To evaluate the effectiveness of a multimodal, symptom-tailored intervention designed to accelerate recovery and increase symptom resolution in children with pPCS at 3 months post-injury.

Main Methods:

  • An open-label, assessor-blinded, randomized clinical trial involving children aged 8-18 years with concussion.
  • Participants were randomized into either the Concussion Essentials (CE) intervention group (multimodal, interdisciplinary treatment) or a usual care (UC) group.
  • The primary outcome was the proportion of participants with resolved pPCS at 3 months post-injury.

Main Results:

  • The study is pre-results, so no findings are available yet.
  • The trial aims to determine if the CE intervention leads to a higher proportion of resolved pPCS compared to UC.
  • Secondary outcomes include return to normal activity, quality of life, and healthcare utilization.

Conclusions:

  • The study will provide crucial data on the efficacy of a novel multimodal intervention for pediatric pPCS.
  • Findings are expected to inform clinical practice and improve recovery trajectories for children experiencing persistent concussion symptoms.
Abstract

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