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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Transcatheter mitral valve replacement: latest advances and future directions
Paul N Fiorilli1, Howard C Herrmann1, Wilson Y Szeto2
1Cardiovascular Medicine Division, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Annals of Cardiothoracic Surgery
|February 12, 2021
Summary
Transcatheter mitral valve replacement offers a promising solution for the most common heart valve disease. Ongoing research and device development are crucial for improving patient outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Mitral regurgitation is the most prevalent global valve disease, frequently occurring as secondary mitral regurgitation in an aging population.
- Understanding the complexities of primary, secondary, and mixed mitral regurgitation is essential for effective treatment strategies.
Purpose of the Study:
- To review the challenges and advancements in transcatheter mitral valve replacement (TMVR).
- To highlight the evolving landscape of transcatheter mitral valve interventions.
Main Methods:
- Review of current transcatheter mitral valve replacement device development, including transapical and transseptal approaches.
- Discussion of anatomical and technical challenges associated with TMVR, such as valve anchoring and left ventricular outflow tract obstruction.
Main Results:
- Several TMVR devices are in early feasibility and pivotal trials, indicating significant progress in the field.
- Transcatheter approaches are being developed to overcome the inherent difficulties of mitral valve replacement.
Conclusions:
- Transcatheter mitral valve replacement is a rapidly advancing field addressing a major unmet need in cardiovascular therapeutics.
- A heart team approach is critical for patient selection and tailoring individualized treatment strategies for mitral valve disease.
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