Related Experiment Video
Updated: Nov 17, 2025
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Dentoalveolar radiation dose following IMRT in oropharyngeal cancer-An observational study
Vinod Patel1, Laia Humbert-Vidan2, Christopher Thomas3
1Oral Surgery Department, Guy's & St Thomas' NHS Foundation Trust, Great Maze Pond, London, SE1 9RT, UK.
Objectives:
This observational study aims to determine individual dental doses in oropharyngeal cancer (OPC) patients managed by intensity modulated radiation treatment (IMRT).
Materials And Methods:
OPC patients treated with IMRT had each tooth individually contoured on post-IMRT CT scans. The mean, maximum and minimum doses were calculated per tooth-based upon patient and tumor demographics (tumor size and nodal status).
Results:
A total of 160 patients were included in this study. Escalating tumor size and nodal status led to an observed increase in Dmean doses to the dentition on the contralateral tumor side. A significant region in both jaws received >30 Gy in this tumor group.
Conclusion:
Tumor demographics were observed to influence RT doses to the dentition and need to be considered when providing a pre-RT dental assessment. The observed dose of >30 Gy in large spans of the dentition and jaws highlights future risk of dental deterioration and ORN with long term survival.
