Related Experiment Video
Updated: Nov 17, 2025
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Central Nervous System Complications of Erdheim-Chester Disease: FDG PET/CT Findings
Nuh Filizoglu1, Salih Ozguven, Tunc Ones
1From the Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.
Insights
Erdheim-Chester disease, a rare histiocytosis, can manifest with central nervous system symptoms. This case highlights the utility of FDG PET/CT in diagnosing this uncommon condition.
Area of Science:
- Histiocytosis
- Neurology
- Radiology
Background:
- Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis.
- Diagnosis relies on imaging and histological findings.
- Commonly presents with bone lesions and multi-organ involvement.
Observation:
- A 19-year-old male presented with progressive polyuria, polydipsia, gait disturbances, and eye pain.
- These symptoms indicated central nervous system involvement.
Findings:
- FDG PET/CT imaging revealed characteristic findings.
- The patient was diagnosed with Erdheim-Chester disease.
Implications:
- FDG PET/CT is a valuable tool for diagnosing Erdheim-Chester disease, especially with CNS manifestations.
- Early diagnosis can guide appropriate management strategies.
- Understanding rare disease presentations is crucial for clinicians.
Abstract:
Erdheim-Chester disease is an uncommon non-Langerhans cell histiocytosis. The diagnosis depends on imaging and histological criteria. The most common presentation is the multiple bone lesions with involvement of at least 1 more organ. We present the FDG PET/CT findings of a 19-year-old man who presented with central nervous system symptoms such as progressive polyuria, polydipsia, gait disturbances, and eye pain and was later diagnosed with Erdheim-Chester disease.
More Related Videos
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
08:55A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
Related Concept Videos
01:29Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
01:25Endocarditis II: Clinical Features of Infective Endocarditis