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Glycated Haemoglobin Levels and Its Effect on Outcomes in Cardiac Surgery

Daniyal Matin Ansari1, Tinotenda Harahwa1, Eyad Abuelgasim2

  • 1St. George's Hospital Medical School, London, United Kingdom.

Brazilian Journal of Cardiovascular Surgery
|February 12, 2021
PubMed

Insights

High blood sugar (HbA1c) levels in cardiac surgery patients are linked to increased complications like infections and kidney failure, but not clearly to death. This review examines these risks.

Area of Science:

  • Cardiology
  • Endocrinology
  • Surgical Outcomes

Background:

  • Diabetes is a common comorbidity in patients undergoing open-heart surgery.
  • Elevated glycated hemoglobin A1c (HbA1c) levels are theorized to impact outcomes.
  • Current literature lacks a clear consensus on HbA1c's effect on perioperative mortality.

Approach:

  • This review synthesizes existing evidence on morbidities and mortalities.
  • Examines the impact of high HbA1c on post-operative outcomes.
  • Focuses on wound infections, cardiovascular events, and renal failure.

Key Points:

  • Elevated HbA1c is associated with increased rates of wound infection.
  • Higher HbA1c levels correlate with greater cardiovascular events and renal failure.
  • A definitive link between high HbA1c and increased perioperative mortality remains unclear.

Conclusions:

  • While high HbA1c may not directly increase mortality, it is linked to significant post-operative morbidities.
  • Managing HbA1c levels in cardiac surgery patients is crucial for reducing complications.
  • Further research is needed to clarify the mortality impact of elevated HbA1c in this population.

Keywords:
Cardiac Surgical ProceduresCardiovascular DiseasesComorbidityDiabetes MellitusGlycated Hemoglobin AMorbidityRenal InsufficiencyWound Infection

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