Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Secondary Active Transport01:32

Secondary Active Transport

8.7K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme "pump" embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
8.7K
Secondary Active Transport01:55

Secondary Active Transport

133.9K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
133.9K
The Movement of Organelles and Vesicles01:43

The Movement of Organelles and Vesicles

5.4K
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
5.4K
Facilitated Transport01:19

Facilitated Transport

142.7K
The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
142.7K
Facilitated Transport01:19

Facilitated Transport

16.6K
The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
16.6K
Electron Transport Chain Components01:29

Electron Transport Chain Components

573
The electron transport chain (ETC) is a crucial metabolic pathway that facilitates energy conversion in prokaryotic and eukaryotic cells. In eukaryotes, the ETC comprises four membrane-associated protein complexes in the inner mitochondrial membrane. In prokaryotes, the ETC in the plasma membrane can vary in composition, with fewer or different complexes depending on the organism and environmental conditions. These complexes transfer electrons from electron donors, such as NADH and FADH2, to...
573

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonadiabatic Dynamics of Photoinduced Hydrogen Dissociation on Plasmonic Au Nanoparticles: How Hot Carrier Excitation Leads to Bond Breaking.

ACS nano·2026
Same author

Infrared Spectroelectrochemical Insights into Rhenium-Based Supramolecular Assemblies for Electron Storage and Transfer.

Inorganic chemistry·2026
Same author

Reductive Dechlorination of Aryl Chlorides Using Hantzsch Ester.

Organic letters·2026
Same author

Captodative Radicals Enable the Coexistence of Monomer and Dimer Single-Molecule Junctions with 100-Fold Difference in Conductance.

Journal of the American Chemical Society·2026
Same author

A Self-Assembled Cage Binds Xenon via Xe-F Dispersion Interactions.

Journal of the American Chemical Society·2026
Same author

Real-Time Electron-Electron Scattering Dynamics in Plasmonic Nanostructures.

ACS nano·2026
Same journal

Gas-Responsive Metal-Organic Frameworks for Adaptive Thermal Energy Storage with Tunable Charge-Discharge Temperatures.

Journal of the American Chemical Society·2026
Same journal

Engineering a Thiamine-Dependent Benzoylformate Decarboxylase for Stereodivergent Radical C(sp<sup>3</sup>)-C(sp<sup>3</sup>) Bond Formation.

Journal of the American Chemical Society·2026
Same journal

Accelerated Directional Proton-Coupled Electron Transfer Enabled by Intrinsic Dipole Field in Biomimetic α-Helical Structure.

Journal of the American Chemical Society·2026
Same journal

Alternating Current-Driven Hydrogen Isotope Labeling of Aliphatic Amines Using 1,3-Propanedithiol as an Efficient Hydrogen Atom Transfer Reagent.

Journal of the American Chemical Society·2026
Same journal

Two-Dimensional van der Waals Polar Metal MoOBr<sub>2</sub>.

Journal of the American Chemical Society·2026
Same journal

Negatively Curved Chiral Bilayer Nanographene.

Journal of the American Chemical Society·2026
See all related articles

Related Experiment Video

Updated: Nov 17, 2025

Introduction to Solid Supported Membrane Based Electrophysiology
19:56

Introduction to Solid Supported Membrane Based Electrophysiology

Published on: May 11, 2013

15.4K

Single-Molecule Charge Transport through Positively Charged Electrostatic Anchors.

Hongliang Chen1, Vitor Brasiliense1,2, Jingshan Mo3

  • 1Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|February 12, 2021
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel electrostatic anchor strategy for robust single-molecule junctions using pyridinium groups. This method enables binary switching in molecular junctions, paving the way for new redox-activated molecular switches.

More Related Videos

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

11.9K
Cargo Loading onto Kinesin Powered Molecular Shuttles
09:00

Cargo Loading onto Kinesin Powered Molecular Shuttles

Published on: November 3, 2010

10.8K

Related Experiment Videos

Last Updated: Nov 17, 2025

Introduction to Solid Supported Membrane Based Electrophysiology
19:56

Introduction to Solid Supported Membrane Based Electrophysiology

Published on: May 11, 2013

15.4K
Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

11.9K
Cargo Loading onto Kinesin Powered Molecular Shuttles
09:00

Cargo Loading onto Kinesin Powered Molecular Shuttles

Published on: November 3, 2010

10.8K

Area of Science:

  • Molecular electronics
  • Nanotechnology
  • Supramolecular chemistry

Background:

  • Charge transport in single-molecule junctions is highly sensitive to the choice of anchoring groups connecting molecular wires to electrodes.
  • Developing robust and efficient anchoring strategies is crucial for realizing functional molecular devices.

Purpose of the Study:

  • To introduce a new anchoring strategy, the electrostatic anchor, utilizing Coulombic interactions for robust gold-molecule connections.
  • To investigate the potential for redox-switching behavior in single-molecule junctions employing this new anchoring method.

Main Methods:

  • Formation of single-molecule junctions using gold electrodes and pyridinium terminal groups to create electrostatic anchors.
  • Electrical characterization of the gold-molecule-gold junctions to assess junction stability and charge transport properties.
  • Investigation of switching behavior in dicationic viologen molecular junctions under electrical bias.

Main Results:

  • The electrostatic anchor, based on Coulombic interaction between gold and pyridinium groups, forms robust molecular junctions.
  • Binary switching behavior was observed in dicationic viologen molecular junctions.
  • The observed switching is attributed to electron injection-induced redox changes between dicationic and radical cationic states.

Conclusions:

  • The electrostatic anchor strategy provides a robust method for forming single-molecule junctions.
  • Electron injection-induced redox switching in single-molecule junctions is demonstrated.
  • This anchoring strategy and switching mechanism offer a foundation for developing novel redox-activated single-molecule switches.