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Related Concept Videos

Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Factors Affecting the Risk of Infection01:26

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
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Transmission-based Precautions II: Airborne and Protective Environment01:25

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Standard Precaution01:26

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Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
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Updated: Nov 17, 2025

Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
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[Less is more… in infectious diseases].

A Fathi1, A Hennigs2, M M Addo2

  • 1Medizinische Klinik und Poliklinik, Sektion Infektiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. a.fathi@uke.de.

Der Internist
|February 13, 2021
PubMed
Summary
This summary is machine-generated.

Overuse in infectious disease diagnostics and treatment contributes to antimicrobial resistance. Implementing antibiotic stewardship and diagnostic measures can reduce overuse and improve patient outcomes.

Keywords:
Antimicrobial stewardshipAsymptomatic bacteriuriaMedical overuseNosocomial infectionsPenicillin allergy

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Area of Science:

  • Infectious Diseases
  • Public Health
  • Antimicrobial Resistance

Background:

  • Antimicrobial resistance is a major public health threat.
  • Falsely indicated antibiotic treatment significantly contributes to antimicrobial resistance.

Purpose of the Study:

  • Identify areas of overuse in infectious disease diagnostics and treatment.
  • Provide recommendations to mitigate overuse and its consequences.

Main Methods:

  • Conducted a literature search of current studies on medical overuse in infectious diseases.
  • Included contributions from international "less is more" initiatives.
  • Focused on areas where reducing diagnostics/therapeutics optimizes patient outcomes.

Main Results:

  • Overuse in infectious disease diagnostics and treatment creates financial burdens.
  • Overuse increases the risk of antimicrobial resistance development.
  • Overuse can lead to adverse patient consequences.

Conclusions:

  • Appropriate antimicrobial agent selection and application are vital for optimal patient care.
  • Diagnostic and antibiotic stewardship programs, with infectious disease specialist input, can reduce overuse and misuse.