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Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

255
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
255
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

2.2K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.2K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

134
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
134
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

149
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
149
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.9K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.9K
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

242
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
242

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Age, Sex, and Outcomes in Heart Failure With Reduced EF: Insights From the VICTORIA Trial.

JACC. Heart failure·2023
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Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.

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Cardiovascular effects of rivaroxaban in heart failure patients with sinus rhythm and coronary disease with and without diabetes: a retrospective international cohort study from COMMANDER-HF.

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Management of Worsening Heart Failure With Reduced Ejection Fraction: JACC Focus Seminar 3/3.

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Evolution of NT-proBNP During Prerandomization Screening in VICTORIA: Implications for Clinical Outcomes and Efficacy of Vericiguat.

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Rationale and design of ENDEAVOR: A sequential phase 2b-3 randomized clinical trial to evaluate the effect of myeloperoxidase inhibition on symptoms and exercise capacity in heart failure with preserved or mildly reduced ejection fraction.

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Related Experiment Video

Updated: Nov 17, 2025

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
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A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

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Heart failure or heart success?

Kanako Teramoto1, Jasper Tromp2,3,4, Carolyn S P Lam2,3,4,5

  • 1Department of Cardiology, St. Marianna University School of Medicine, Kanagawa, Japan.

Cardiovascular Research
|February 13, 2021
PubMed
Summary

No abstract available in PubMed .

Keywords:
Cardiac myosinFerric carboxymaltoseSotagliflozinHFrEF

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