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A novel computational method for assigning weights of importance to symptoms of COVID-19 patients
Mohammad A Alzubaidi1, Mwaffaq Otoom1, Nesreen Otoum2
1Department of Computer Engineering, Yarmouk University, Irbid, 21163, Jordan.
Insights
Identifying key symptoms of coronavirus disease 2019 (COVID-19) is crucial. This study found that fever, cough, fatigue, sore throat, and shortness of breath are the most significant indicators of COVID-19.
Area of Science:
- Medical Informatics
- Epidemiology
- Data Science
Background:
- The COVID-19 pandemic presents a challenge with diverse patient symptoms.
- Understanding common symptoms and their importance is critical for diagnosis and management.
Purpose of the Study:
- To identify and rank the most important symptoms of COVID-19.
- To evaluate the effectiveness of feature selection algorithms in analyzing COVID-19 symptom data.
Main Methods:
- A COVID-19 dataset of 738 confirmed cases was preprocessed.
- Six feature selection algorithms, including a novel Variance Based Feature Weighting (VBFW) method, were applied.
- Symptom importance was ranked and quantitatively measured.
Main Results:
- Aggregated results from five algorithms identified Fever/Cough, Fatigue, Sore Throat, and Shortness of Breath as key symptoms.
- The novel VBFW algorithm ranked Fever (75%) and Cough (39.8%) as highly indicative.
- VBFW achieved 92.1% accuracy in a one-class SVM model and 100% NDCG@5.
Conclusions:
- Fever, Cough, Fatigue, Sore Throat, and Shortness of Breath are important indicators of COVID-19.
- The VBFW algorithm highlights Fever and Cough as particularly significant symptoms in the analyzed dataset.
Background And Objective:
The novel coronavirus disease 2019 (COVID-19) is considered a pandemic by the World Health Organization (WHO). As of April 3, 2020, there were 1,009,625 reported confirmed cases, and 51,737 reported deaths. Doctors have been faced with a myriad of patients who present with many different symptoms. This raises two important questions. What are the common symptoms, and what are their relative importance?
Methods:
A non-structured and incomplete COVID-19 dataset of 14,251 confirmed cases was preprocessed. This produced a complete and organized COVID-19 dataset of 738 confirmed cases. Six different feature selection algorithms were then applied to this new dataset. Five of these algorithms have been proposed earlier in the literature. The sixth is a novel algorithm being proposed by the authors, called Variance Based Feature Weighting (VBFW), which not only ranks the symptoms (based on their importance) but also assigns a quantitative importance measure to each symptom.
Results:
For our COVID-19 dataset, the five different feature selection algorithms provided different rankings for the most important top-five symptoms. They even selected different symptoms for inclusion within the top five. This is because each of the five algorithms ranks the symptoms based on different data characteristics. Each of these algorithms has advantages and disadvantages. However, when all these five rankings were aggregated (using two different aggregating methods) they produced two identical rankings of the five most important COVID-19 symptoms. Starting from the most important to least important, they were: Fever/Cough, Fatigue, Sore Throat, and Shortness of Breath. (Fever and cough were ranked equally in both aggregations.) Meanwhile, the sixth novel Variance Based Feature Weighting algorithm, chose the same top five symptoms, but ranked fever much higher than cough, based on its quantitative importance measures for each of those symptoms (Fever - 75 %, Cough - 39.8 %, Fatigue - 16.5 %, Sore Throat - 10.8 %, and Shortness of Breath - 6.6 %). Moreover, the proposed VBFW method achieved an accuracy of 92.1 % when used to build a one-class SVM model, and an NDCG@5 of 100 %.
Conclusions:
Based on the dataset, and the feature selection algorithms employed here, symptoms of Fever, Cough, Fatigue, Sore Throat and Shortness of Breath are important symptoms of COVID-19. The VBFW algorithm also indicates that Fever and Cough symptoms were especially indicative of COVID-19, for the confirmed cases that are documented in our database.
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